Two sample MR report
CD55_Monocyte (Mono) against finn-b-ASTHMA_ALLERG_EXMORE
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 5 | 0.1609372 | 0.3951119 | 0.7110939 |
| Weighted median | 5 | 0.1148811 | 0.0444403 | 0.0097360 |
| Inverse variance weighted | 5 | 0.1123616 | 0.0353130 | 0.0014632 |
| Simple mode | 5 | 0.1155603 | 0.0534438 | 0.0966422 |
| Weighted mode | 5 | 0.1166977 | 0.0560996 | 0.1060003 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 1.025138 | 3 | 0.7951697 |
| Inverse variance weighted | 1.040374 | 4 | 0.9036134 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0205765 | 0.1666985 | 0.9095678 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0001427 | 0 | TRUE | 0.2575397 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
